Street-Based Hepatitis C Treatment and Patient Experiences Among Adults Experiencing Unsheltered Homelessness - Summary - MDSpire

Hepatitis C Management in Street Settings: Insights from Adults Facing Unsheltered Homelessness

  • By

  • Alizée Natsoulis

  • Claire Nussbaum

  • Lauren Howard

  • Daphne Achilles

  • Korrinne Yurick

  • Camilo Zaks

  • Alexis Coulourides Kogan

  • July 16, 2026

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Objective:

To explore the perspectives of patients who engaged in street-based treatment for HCV, assess treatment outcomes, and compare these findings to clinicians’ predictions.

Approach:
  • Study Design: Conducted one-time, in-person, semistructured interviews with patients engaged in street-based HCV treatment through a street medicine program from June to August 2023.
  • Participants: 15 adult patients served by USC Street Medicine who initiated street-based HCV treatment after a positive screen.
  • Data Collection: Interviews followed a 4-item semistructured guide, were audio-recorded, transcribed verbatim, and analyzed.
Key Findings:
  • People experiencing homelessness have a high prevalence of HCV, with estimates ranging from 10% to 53%.
  • The USC Street Medicine program has provided full-spectrum primary care to unsheltered individuals since 2018.
  • Medi-Cal Rx removed restrictions on HCV treatment, enabling better access for patients.
Interpretation:

Limitations:
  • Small sample size of 15 participants may limit generalizability.
  • Participants were primarily from a single geographic area (Los Angeles County).
Conclusion:

Sources:

Original Source(s)

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