To evaluate outcome data for patients with malignant orbital tumors treated at Haukeland University Hospital over a 22 year period and compare them with existing literature.
Approach:
Study Design: Retrospective review of medical records from patients with malignant orbital tumors treated from 1999 to 2020.
Data Collection: Patients were identified through hospital database searches; data on clinical features, management, and outcomes were recorded.
Statistical Analysis: Survival endpoints were analyzed using Kaplan–Meier plots and log-rank tests.
Key Findings:
76 patients included: 54% females, 46% males; median age at diagnosis was 64 years.
Incidence of malignant orbital tumors in Western Norway was 0.30 per 100,000 inhabitants.
Most common tumor types: secondary invading tumors (46%), lymphoproliferative (24%), metastatic (16%), primary orbital tumors (14%).
Overall disease-specific 5-year survival was 59%, with significant differences between subgroups: lymphoproliferative diseases 82%, primary orbital tumors 80%, secondary invading tumors 46%, orbital metastases 39%.
Interpretation:
Limitations:
Study conducted at a single low-volume center, which may affect generalizability.
Limited number of patients in each tumor category may restrict statistical analyses.
by Bendik Alvheim Sundfjord, Julie Selvik Bentzon, Signe Johnsen Landa, Svein Arthur Jensen, Dorota Goplen, Jon Espen Dale, Stein Lybak, Hans Olav Ueland, Eyvind Rødahl
