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Probiotics Are DED Friendly

Using probiotics for Dry Eye

  • By

  • Alun Evans

  • August 1, 2023

  • 3 min

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Objective:

To investigate the effects of the probiotic Limosilactobacillus reuteri DSM 17938 on dry eye disease (DED) in mice models.

Approach:
  • Study Design: Mice were colonized with gut bacteria from Sjögren syndrome patients and healthy individuals, then treated with antibiotics followed by oral administration of the probiotic strain under dry conditions.
  • Evaluation: After five days, the mice's eyes were examined for signs of DED, comparing the probiotic group to a control group treated with saline.
Key Findings:
  • Mice receiving the probiotic had healthier corneal surfaces.
  • Probiotic treatment resulted in more goblet cells in the ocular tissue.
  • Gut bacteria from healthy individuals may protect against dry eye symptoms.
Interpretation:

Limitations:
  • The study was conducted in mice models, and further research is needed to confirm findings in humans.
  • The mechanism of action of the probiotic in the context of eye health is still under investigation.
Conclusion:

Sources:

Original Source(s)

Probiotics Are DED Friendly

  • by Alun Evans

  • August 1, 2023

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