Influencing factors and path analysis of posttraumatic growth in patients with autoimmune diseases - Summary - MDSpire

Influencing factors and path analysis of posttraumatic growth in patients with autoimmune diseases

  • By

  • Zheyuan Xia

  • Leran Tang

  • Ting Yao

  • Qiao Hu

  • Xiao Wang

  • Xiang Wang

  • June 10, 2026

  • 0 min

Share

Objective:

To construct a structural equation model of posttraumatic growth in patients with autoimmune diseases, guided by the Transactional Model of Stress and Coping, and examine the associative pathways among key factors.

Approach:
    Key Findings:
    • The total score of posttraumatic growth was 52.20 ± 13.87.
    • The structural equation model accounted for 49.3% of the variance in posttraumatic growth.
    • Fear of disease progression was directly positively associated with posttraumatic growth (β = 0.290).
    • Three significant mediating pathways were identified: fear of disease progression → social support → posttraumatic growth; fear of disease progression → patient-reported disease activity → posttraumatic growth; fear of disease progression → avoidance coping → posttraumatic growth.
    • The mediating effects of resignation coping and illness perception were not statistically significant, indicating the need for further exploration of these pathways.
    Interpretation:

    Fear of disease progression is positively associated with posttraumatic growth, with indirect associations through social support and avoidance coping, highlighting the complexity of these relationships.

    Limitations:
    • The study's cross-sectional design limits the ability to infer causal relationships.
    • The sample was limited to patients from three hospitals in Anhui Province, which may affect generalizability and the robustness of findings.
    Conclusion:

    Addressing fear of disease progression and enhancing social support through targeted interventions may promote posttraumatic growth in patients with autoimmune diseases.

Original Source(s)

Related Content