To characterize the association between intraoperative mean arterial pressure, central venous pressure, and renal near infrared spectroscopy with acute kidney injury after pediatric heart transplant.
Approach:
Study Design: Single-center, retrospective study at Ann & Robert H. Lurie Children’s Hospital of Chicago, focusing on pediatric patients who underwent heart transplantation.
Data Collection: Patient characteristics, operative data, and intraoperative physiologic data were collected from electronic health records and perfusion/anesthesia records.
Statistical Analyses: Continuous and categorical variables were analyzed using Mann–Whitney U test and Fisher’s exact test, respectively. Receiver operating curve analyses were performed to evaluate the discriminative ability of various intraoperative variables for postoperative ac…
Key Findings:
The incidence of acute kidney injury after pediatric heart transplant ranges from 49% to 66%, as reported in various studies.
Intraoperative mean arterial pressure, central venous pressure, and renal near infrared spectroscopy were evaluated for their association with acute kidney injury.