To evaluate the feasibility and safety of direct amoxicillin challenges for penicillin allergy testing in pediatric group visits.
Key Findings:
120 children were referred for the amoxicillin challenge group visit, with 61 challenges completed.
95% of participants tolerated the challenge with no severe reactions.
Mild cutaneous reactions occurred in 3 patients, all resolved without significant intervention.
Interpretation:
The study supports the safety and efficacy of direct amoxicillin challenges in a pediatric primary care setting, indicating a potential for broader implementation of penicillin allergy testing.
Limitations:
Small sample size with only 61 completed challenges.
Retrospective design may limit generalizability.
Conclusion:
Direct amoxicillin challenges can effectively delabel penicillin allergies in children during group visits, warranting further studies for broader application.
