Temporal changes in the risk of six-month post-COVID symptoms: a national population-based cohort study - Summary - MDSpire

Temporal changes in the risk of six-month post-COVID symptoms: a national population-based cohort study

  • By

  • Anne Pastorello

  • Laurence Meyer

  • Joël Coste

  • Camille Davisse-Paturet

  • Xavier de Lamballerie

  • Maria Melchior

  • Sophie Novelli

  • Delphine Rahib

  • Nathalie Bajos

  • Cécile Vuillermoz

  • Jeanna-Eve Franck

  • Carmelite Manto

  • Alexandra Rouquette

  • Josiane Warszawski

  • EpiCov study group

  • July 3, 2024

  • 0 min

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Objective:

To explore the variation in the risk of post-COVID symptoms in 2020, comparing the first and second waves of COVID-19 in France, and to identify associated sociodemographic and health-related risk factors.

Key Findings:
  • The risk of post-COVID symptoms was 14.6% during the first wave (March-May 2020) compared to 7.0% during the second wave (September-November 2020).
  • Adjusted relative risk for post-COVID symptoms was 1.36, indicating a significantly higher risk during the first wave.
  • Higher risk was associated with baseline physical conditions and increased acute symptoms; during the first wave, women and individuals with baseline mental conditions also showed increased risk.
Interpretation:

The findings suggest that the risk of developing post-COVID symptoms was significantly higher during the first wave of the pandemic, likely due to heightened anxiety and limited healthcare access at that time.

Limitations:
  • The study may not fully account for all confounding factors influencing post-COVID symptoms.
  • Data collection was limited to specific time frames and may not reflect long-term trends.
Conclusion:

The risk of six-month post-COVID symptoms was notably higher during the first wave of the pandemic in France, highlighting the impact of the pandemic context on health outcomes.

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