To evaluate the effectiveness of three outreach methods (mailed brochure, email, SMS text message) and clinic workflow variations on genetic testing participation among high-risk patients.
Key Findings:
Overall genetic testing following outreach was low, less than 3%, and did not differ by outreach method, highlighting a need for improved engagement strategies.
The different building workflow was associated with a lower order rate than the same building workflow (IRR = 0.72, 95% CI = 0.65–0.80), indicating potential barriers in access.
Differences in order rates by patient characteristics were larger in the different building workflow, suggesting disparities in access.
Interpretation:
While outreach methods yielded low engagement, low-cost methods like email are feasible, and point-of-care access is critical for improving participation and equity. Implementing point-of-care strategies could enhance patient engagement.
Limitations:
Low overall participation rates may limit the generalizability of findings.
The study was conducted in a specific health system, which may not reflect broader populations.
Potential biases in patient selection may affect the results.
Conclusion:
Health systems should prioritize same-day testing and provider capacity to expand access and reduce barriers to genetic testing.
