Comparison of preoperative and intraoperative cultures for predicting postoperative urinary tract infections following supine PCNL - Summary - MDSpire

Comparison of preoperative and intraoperative cultures for predicting postoperative urinary tract infections following supine PCNL

  • By

  • Ozgur, Gunal

  • Dorucu, Dogancan

  • Duran, Orhan Bugra

  • Gokmen, Ersin

  • Senoglu, Yusuf

  • Cam, Haydar Kamil

  • Sener, Tarik Emre

  • March 2, 2026

  • 0 min

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Objective:

To compare the predictive value of preoperative midstream urine culture (PMUC), intraoperative renal pelvic urine culture (RPUC), and stone culture (SC) for postoperative urinary tract infections (UTIs) following supine-PCNL, highlighting the clinical significance of these comparisons.

Key Findings:
  • Postoperative UTI occurred in 14.1% of patients (n = 33).
  • Postoperative fever was noted in 12.4% of patients, significantly higher in UTI-positive patients (72.7%).
  • No significant differences in age, BMI, diabetes presence, stone size, or surgery laterality between UTI-positive and UTI-negative patients.
  • Higher proportion of female patients in the UTI-positive group (60.6%).
  • UTI occurrence was more common among patients with an ASA score of 3.
Interpretation:

Intraoperative cultures (RPUC and SC) may provide better predictive value for postoperative UTIs compared to PMUC, particularly in identifying at-risk patients, which could inform tailored antibiotic prophylaxis.

Limitations:
  • Retrospective design may introduce selection bias, potentially affecting the reliability of the findings.
  • Limited generalizability due to single-center study, which may not reflect broader populations.
  • Potential confounding factors not fully controlled, which could influence the results.
Conclusion:

Intraoperative cultures are crucial for predicting postoperative UTIs after PCNL, emphasizing the need for tailored antibiotic prophylaxis based on culture results, and aligning with existing literature on the topic.

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