Association of residential altitude with pure-tone hearing thresholds in plateau residents aged ≤50 years: a cross-sectional study - Summary - MDSpire

Association of residential altitude with pure-tone hearing thresholds in plateau residents aged ≤50 years: a cross-sectional study

  • By

  • Qingping Zhang

  • Guoqiang Jia

  • Shanhong Li

  • Haiyan Liu

  • Yulin Ma

  • Wenqi Du

  • Juan Ye

  • Ying Zhang

  • Tana Wuren

  • Yi Wang

  • Bin Guo

  • June 16, 2026

  • 0 min

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Objective:

To investigate the association between long-term residential altitude strata and characteristics of pure-tone hearing thresholds in plateau residents aged 50 years or younger.

Approach:
    Key Findings:
    • Unadjusted analyses showed significant differences in hearing thresholds at higher frequencies, indicating a potential impact of altitude.
    • In fully adjusted models, only PTA at 8 kHz remained statistically significant between lower- and middle-altitude strata, highlighting a specific frequency of concern.
    • No stable linear trend was supported in continuous-altitude models, suggesting complexity in the relationship.
    Interpretation:

    Hearing-threshold differences were more pronounced at higher frequencies in unadjusted analyses; after adjustment, the most robust association was observed at 8 kHz, indicating a need for targeted interventions.

    Limitations:
    • The study focused on residents aged 50 years or younger, limiting generalizability to older populations and necessitating further research.
    • Potential confounding factors, such as environmental noise exposure and individual health conditions, may not have been fully accounted for despite adjustments.
    Conclusion:

    The study highlights the need for further research on the impact of altitude on auditory function, particularly in long-term residents, and suggests exploring the effects on older populations.

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