Objective:

To evaluate transrectal oocyte retrieval (TROR) and compare it with conventional transvaginal oocyte retrieval (TVOR) for patients with intact hymens.

Approach:

• Study Design: A prospective observational study involving 120 patients undergoing oocyte cryopreservation, divided into two groups: TROR and TVOR.
• Data Collection: Comparison of follicle and oocyte retrieval counts, with regression analyses to evaluate the impact of age, BMI, AMH, anesthesia duration, procedural time, and peak E2.

Key Findings:

• Number of oocytes negatively correlated with age in both TROR and TVOR groups (r = -0.10, P = 0.22; r = -0.55, P < 0.001).
• Number of oocytes negatively correlated with BMI in both groups (r = -0.20, P = 0.03; r = -0.12, P = 0.19).
• In TROR, number of oocytes positively correlated with AMH level (r = 0.80, P < 0.001), anesthesia time (r = 0.56, P < 0.001), surgery time (r = 0.55, P < 0.001), peak E2 (r = 0.81, P < 0.001), and number of follicles (r = 0.69, P < 0.001).
• In TVOR, number of oocytes showed significant correlation with AMH (r = 0.40, P < 0.01), anesthesia time (r = 0.73, P < 0.001), surgery time (r = 0.74, P < 0.001), peak E2 (r = 0.80, P < 0.001), and number of follicles (r = 0.85, P < 0.001).

Interpretation:

Transvaginal oocyte collection is the standard method, but TROR is a safe alternative for patients with intact hymens, particularly in culturally sensitive regions.

Limitations:

• Limited research on TROR prior to this study.
• Study conducted in a specific cultural context may limit generalizability.

Conclusion:

Both TROR and TVOR are viable methods for oocyte retrieval, with TROR providing a culturally sensitive option for certain patients.