Impact of a virtual reality program on the cognitive and psycho-emotional state of seniors with mild cognitive impairment - Summary - MDSpire

Impact of a virtual reality program on the cognitive and psycho-emotional state of seniors with mild cognitive impairment

  • By

  • Natalia V. Sharashkina

  • Olga N. Tkacheva

  • Elen A. Mkhitaryan

  • Nadezhda G. Dudchenko

  • Nadezhda K. Runikhina

  • July 15, 2026

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Objective:

To assess the efficacy of a virtual reality-based program in improving cognition and affect in patients with mild cognitive impairment during inpatient treatment.

Approach:
  • Study Design: Randomized controlled trial comparing an experimental group receiving virtual reality intervention alongside standard treatment with a control group receiving standard treatment only.
  • Participants: Sixty-two patients aged 60 to 89 with mild cognitive impairment were enrolled, with 31 in each group.
  • Assessment Tools: Cognitive function was measured using the Montreal Cognitive Assessment (MoCA), and emotional well-being was assessed using the Geriatric Depression Scale (GDS-15) and the Hospital Anxiety and Depression Scale (HADS).
Key Findings:
  • Both groups showed significant improvements in cognitive function and reduction in depression symptoms after 2 weeks.
  • The experimental group had a greater improvement in MoCA scores (2.6 ± 2.1) compared to the control group (1.3 ± 1.5).
  • The experimental group also showed a more significant reduction in depressive symptoms on the HADS depression subscale (-1.6 ± 3.2 vs -0.3 ± 1.5).
  • Anxiety subscale improvements were statistically insignificant between groups.
Interpretation:

Limitations:
  • Small sample size.
  • Lack of blinding.
  • No replacement intervention in the control group.
Conclusion:

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