To evaluate the predictive value of the C-reactive protein to albumin ratio (CRP/albumin) and systemic immune-inflammation index (SII) in the context of retinal vein occlusion (RVO) assessment.
Key Findings:
The CRP/albumin ratio was significantly higher in RVO patients compared to controls, indicating its potential as a diagnostic tool.
The optimal cut-off value for CRP/albumin ratio for RVO estimation was 0.42, with 79% sensitivity and 55% specificity, suggesting moderate diagnostic accuracy.
Central macular thickness (CMT) and subfoveal choroidal thickness (SCT) were significantly higher in the RVO group, reinforcing the association between inflammation and RVO.
Interpretation:
The CRP/albumin ratio may serve as a useful inflammatory marker in assessing RVO, potentially aiding in its diagnosis, and aligns with findings from previous studies.
Limitations:
Small sample size of 34 patients in each group limits the statistical power.
Retrospective design may introduce selection bias, affecting the reliability of the findings.
Conclusion:
The CRP/albumin ratio is a promising marker for RVO assessment, warranting further investigation in larger cohorts to validate its clinical utility.
