A visual mining analysis of middle meningeal embolization and other factors associated with recurrence requiring re-operation in subdural hematomas: a single-center series - Summary - MDSpire

A visual mining analysis of middle meningeal embolization and other factors associated with recurrence requiring re-operation in subdural hematomas: a single-center series

  • By

  • Marco Battistelli

  • Marika Vezzoli

  • Iacopo Valente

  • Massimo Benenati

  • Giuseppe Garignano

  • Andrea Alexandre

  • Ludovico Agostini

  • Samuele Santi

  • Ottavia Giovinazzo

  • Leonardo Nardini

  • Federico Costa

  • Giorgio Quintino D’Alessandris

  • Manuela D’Ercole

  • Alessandro Izzo

  • Alessandro Rapisarda

  • Francesco Signorelli

  • Nicola Montano

  • Simona Gaudino

  • Alessandro Olivi

  • Alessandro Pedicelli

  • Filippo Maria Polli

  • Francesco Doglietto

  • December 20, 2025

  • 0 min

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Objective:

To investigate factors associated with recurrence requiring reoperation in chronic subdural hematomas (cSDH), including the role of middle meningeal artery embolization (MMAE) as a potential treatment adjunct.

Key Findings:
  • Recurrence rates of cSDH can reach up to 50%, influenced by various factors, highlighting the need for improved management strategies.
  • Preoperative volume greater than 130 mL and postoperative residual volume greater than 80 mL are associated with increased recurrence risk, indicating the importance of careful preoperative assessment.
  • Preoperative platelet count below 157 × 10^9/L is a significant predictor of recurrence, suggesting the need for monitoring coagulation profiles.
Interpretation:

The study highlights the importance of various clinical and radiological factors in predicting cSDH recurrence, emphasizing the potential role of MMAE as a treatment adjunct, which may improve patient outcomes.

Limitations:
  • Single-center study may limit generalizability.
  • Retrospective design may introduce selection bias, and confounding factors may not be fully accounted for.
Conclusion:

MMAE may reduce recurrence rates in cSDH when used alongside standard surgical techniques, warranting further investigation in larger, multicenter studies to validate these findings.

Original Source(s)

A visual mining analysis of middle meningeal embolization and other factors associated with recurrence requiring re-operation in subdural hematomas: a single-center series

  • by Marco Battistelli, Marika Vezzoli, Iacopo Valente, Massimo Benenati, Giuseppe Garignano, Andrea Alexandre, Ludovico Agostini, Samuele Santi, Ottavia Giovinazzo, Leonardo Nardini, Federico Costa, Giorgio Quintino D’Alessandris, Manuela D’Ercole, Alessandro Izzo, Alessandro Rapisarda, Francesco Signorelli, Nicola Montano, Simona Gaudino, Alessandro Olivi, Alessandro Pedicelli, Filippo Maria Polli, Francesco Doglietto

  • December 20, 2025

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