Objective:

To identify factors associated with longitudinal supportive care needs (SCN) and examine the prognostic value of SCN in patients with advanced liver cancer.

Approach:

Key Findings:

• Follow-up time, treatment response, HADS score, KPS score, ZBI score, education level, economic burden, and Child-Pugh grade were significantly associated with longitudinal SCNS total score.
• Progressive disease (PD) correlated with higher SCNS total score, while partial response (PR) correlated with lower SCNS total score.
• Higher SCN was significantly associated with increased mortality risk; each 1-SD increase in baseline SCNS total score was linked to a hazard ratio (HR) of 1.95 (95% CI: 1.44–2.65).
• The association remained significant in various survival models, indicating SCN as a dynamic prognostic indicator.

Interpretation:

Limitations:

• The study was conducted at a single center, which may limit generalizability.
• The sample size may not be large enough to capture all variations in SCN and survival outcomes.

Conclusion:

Attribution Notice

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