Analgesic Effects of Intraperitoneal Bupivacaine Following Laparoscopic Bariatric Surgery: A Randomized Clinical Trial - Summary - MDSpire

Analgesic Effects of Intraperitoneal Bupivacaine Following Laparoscopic Bariatric Surgery: A Randomized Clinical Trial

  • By

  • Sherif-Abd AlSayed Abd AlRahman Taie

  • Amir K. Abosayed

  • Ahmed-Yahia Abd ElDayem

  • Amr Mohamed AbdelFattah Ayad

  • July 1, 2026

  • 0 min

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Objective:

To evaluate the efficacy of weight-standardized intraperitoneal instillation of bupivacaine in patients undergoing laparoscopic bariatric surgery and its effects on postoperative pain outcomes.

Approach:
  • Study Design: A randomized clinical trial involving ninety adult patients with severe obesity undergoing various laparoscopic bariatric procedures.
  • Intervention: Patients received either 0.2% bupivacaine or normal saline instilled intraperitoneally at the end of surgery.
  • Pain Assessment: Postoperative pain was assessed using the Visual Analogue Scale (VAS) at multiple time points post-surgery.
Key Findings:
  • Intraperitoneal bupivacaine significantly reduced postoperative pain scores compared to normal saline, according to the study results.
  • Patients receiving bupivacaine required fewer rescue analgesics postoperatively, as indicated by the findings.
  • The study demonstrated the safety of the bupivacaine dosage used in the obese population.
Interpretation:

The study findings indicate that intraperitoneal bupivacaine is effective in managing postoperative pain in patients undergoing laparoscopic bariatric surgery.

Limitations:
  • The study was conducted at a single institution, which may limit generalizability.
  • The sample size may not be sufficient to detect rare complications.
Conclusion:

Intraperitoneal bupivacaine is an effective method for pain relief after laparoscopic bariatric surgery.

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