To establish a standardized transition-of-care framework for pediatric patients with inborn errors of immunity (IEI) as they move to adult healthcare services, while addressing psychosocial aspects.
Key Findings:
Insufficient transition practices lead to medical complications, diminished long-term outcomes, and increased psychosocial distress.
A structured transition model can promote treatment adherence, care continuity, and address psychosocial needs.
Immunoglobulin replacement therapy options should be tailored to patient needs and developmental stages.
Interpretation:
The proposed framework aims to bridge the gap between pediatric and adult healthcare systems, minimizing care discontinuity, enhancing long-term disease management for individuals with IEI, and emphasizing the importance of psychosocial support.
Limitations:
Dependence on multidisciplinary resources may limit implementation.
Lack of prospective validation for the proposed transition model.
Potential impact of insufficient training for adult providers on the transition.
Conclusion:
The framework is intended to be flexible for various healthcare environments and highlights the need for future research to assess its impact on clinical outcomes, particularly regarding psychosocial factors.
