Laparoscopic sacrocolpopexy with mesh fixation: a randomized trial comparing synthetic cyanoacrylate glue to sutures - Summary - MDSpire

Laparoscopic sacrocolpopexy with mesh fixation: a randomized trial comparing synthetic cyanoacrylate glue to sutures

  • By

  • Gery Lamblin

  • Graziella Moufawad

  • Cécile Becque

  • Chloé Miguet

  • Stéphanie Moret

  • Sophie Warembourg

  • Erdogan Nohuz

  • Charles-André Philip

  • October 7, 2025

  • 0 min

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Objective:

To compare operative time, success rate, and outcomes between mesh fixation using synthetic glue and conventional laparoscopic suturing during laparoscopic sacrocolpopexy, focusing on primary outcomes such as operative time and success rates.

Key Findings:
  • Synthetic glue was found to be safe and effective for mesh fixation.
  • Glue fixation reduced operative time compared to suturing, with a statistically significant difference.
  • Both methods showed comparable success rates and outcomes.
Interpretation:

The use of synthetic cyanoacrylate glue in laparoscopic sacrocolpopexy may simplify the procedure and reduce operative time without compromising success rates.

Limitations:
  • The study was limited to a single center, which may affect generalizability to broader populations.
  • Long-term outcomes beyond 24 months were not assessed, which limits understanding of durability.
Conclusion:

Synthetic glue offers a viable alternative to sutures for mesh fixation in laparoscopic sacrocolpopexy, potentially enhancing surgical efficiency and improving patient outcomes.

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