Results of the Latin American Bone Marrow Transplantation Society (LABMT) activity survey 2019-2022: the impact of the COVID-19 pandemic and the increase in related haploidentical donors - Summary - MDSpire

Results of the Latin American Bone Marrow Transplantation Society (LABMT) activity survey 2019-2022: the impact of the COVID-19 pandemic and the increase in related haploidentical donors

  • By

  • Sebastian Galeano

  • Carmem Bonfim

  • Amado Karduss

  • Gregorio Jaimovich

  • Andrés Gómez-De León

  • Gustavo Bettarello

  • Anderson Simione

  • Cinthya Correa

  • Helen Baldomero

  • Daniel Neumann

  • Ana Lisa Basquiera

  • Mariano Berro

  • Guillermina Remaggi

  • Ariel Amaru

  • Fernando Barroso

  • Adriana Seber

  • Francisco Barriga

  • Julia Palma

  • Bárbara Puga

  • Matías Sánchez

  • Juan Manuel Herrera

  • Calixto Hernández

  • David Gómez-Almaguer

  • Félix Gaytán Morales

  • Guillermo J. Ruiz-Argüelles

  • Ninotzka Mendoza

  • María Liz Benítez

  • Alfredo Wong

  • Carolina Pagés

  • Marcos Hernández

  • Dietger Niederwieser

  • Damiano Rondelli

  • Cristóbal Frutos

  • April 18, 2025

  • 0 min

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Objective:

To report on hematopoietic stem cell transplantation (HCT) activity in Latin America from 2019 to 2022, focusing on the impact of COVID-19 and trends in haploidentical donors, emphasizing their increasing relevance.

Key Findings:
  • Total of 6767 HCT reported in 2022, with 39% being alloHCT and 61% autoHCT, reflecting a shift in donor preferences.
  • Pediatric HCT comprised 1121 cases, with 82% alloHCT and 18% autoHCT, indicating a strong reliance on alloHCT in younger populations.
  • Adult HCT totaled 5646, with 31% alloHCT and 69% autoHCT, suggesting a trend towards more autoHCT in adults.
  • Transplant rate in 2022 was 103 HCT per 10 million population, a critical metric for assessing healthcare access.
Interpretation:

The data indicates a significant volume of HCT activity in Latin America, with a notable prevalence of autoHCT over alloHCT, and highlights the increasing role of haploidentical donors, particularly in the context of the COVID-19 pandemic.

Limitations:
  • Survey responses were not received from all transplant centers, potentially underrepresenting total activity and skewing results.
  • Data on additional HCT beyond the first transplant was not included, limiting the comprehensiveness of the findings.
Conclusion:

The survey provides valuable insights into HCT trends in Latin America during the COVID-19 pandemic, emphasizing the importance of haploidentical donors in the region and suggesting areas for future research.

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