Adjuvant Chemoradiotherapy or Chemotherapy After D2 Gastrectomy in Gastric Cancer: A Randomized Clinical Trial - Summary - MDSpire

Adjuvant Chemoradiotherapy or Chemotherapy After D2 Gastrectomy in Gastric Cancer: A Randomized Clinical Trial

  • By

  • Xin Wang

  • Ouying Yan

  • Jitao Zhou

  • Feng Wen

  • Yali Shen

  • Zhiping Li

  • Qiu Li

  • Wenling Wang

  • Xiaohong Cai

  • Shisheng Tan

  • Zi Wang

  • Qing Qiao

  • Dan Cao

  • Meng Qiu

  • Jiyan Liu

  • Hongfeng Gou

  • Ming Liu

  • Cheng Yi

  • Yu Yang

  • Qing Zhu

  • Deyun Luo

  • Yaqin Zhao

  • Ye Chen

  • Shang Wang

  • Qiaoli Wang

  • Ke Cheng

  • Min Ren

  • Xin Liu

  • Feng Xu

  • Feng Bi

  • June 15, 2026

  • 0 min

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Objective:

To assess whether the addition of radiotherapy (RT) to the SOX chemotherapy regimen increases disease-free survival (DFS) in patients with T4 or node-positive gastric cancer after D2 gastrectomy.

Key Findings:
  • Adjuvant chemotherapy significantly improved survival compared to surgery alone in prior studies.
  • The ARTIST trial suggested that adjuvant RT may improve DFS in lymph node-positive patients after D2 resection.
  • The ARTIST 2 trial indicated no significant difference in efficacy between chemotherapy alone and concurrent CRT after D2 gastrectomy.
Interpretation:

Remove unsupported conclusions and rephrase to reflect the ongoing investigation without editorializing.

Limitations:
  • Ensure limitations are directly sourced or attributed.
Conclusion:

Revise to eliminate unsupported claims and reflect only the findings from the study.

Original Source(s)

Adjuvant Chemoradiotherapy or Chemotherapy After D2 Gastrectomy in Gastric Cancer: A Randomized Clinical Trial

  • by Xin Wang, Ouying Yan, Jitao Zhou, Feng Wen, Yali Shen, Zhiping Li, Qiu Li, Wenling Wang, Xiaohong Cai, Shisheng Tan, Zi Wang, Qing Qiao, Dan Cao, Meng Qiu, Jiyan Liu, Hongfeng Gou, Ming Liu, Cheng Yi, Yu Yang, Qing Zhu, Deyun Luo, Yaqin Zhao, Ye Chen, Shang Wang, Qiaoli Wang, Ke Cheng, Min Ren, Xin Liu, Feng Xu, Feng Bi

  • June 15, 2026

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