Afferent loop syndrome secondary to recurrent pancreatic adenocarcinoma post-Whipple procedure: case report
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By
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Justin Baik
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Neil Hughes
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Vladimir Ferrer
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June 15, 2026
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Objective:
To present a case of afferent loop syndrome (ALS) following pancreaticoduodenectomy due to recurrent pancreatic adenocarcinoma.
Approach:
Key Findings:
- ALS is a rare but serious complication post-Whipple surgery, often due to recurrent malignancy.
- Persistent watery diarrhea can precede acute obstruction, complicating diagnosis.
- Endoscopic decompression with self-expanding metal stents is an effective palliative strategy.
Interpretation:
Limitations:
- The case highlights a single patient experience, limiting generalizability.
- Only a few confirmed ALS cases from pancreatic cancer recurrence have been reported.
Conclusion: