Occupational burnout and risk of suicidality in healthcare professionals: a PRISMA-guided systematic review - Summary - MDSpire

Occupational burnout and risk of suicidality in healthcare professionals: a PRISMA-guided systematic review

  • By

  • Alexandru Ungurianu

  • Virginia Marina

  • July 14, 2026

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Objective:

To synthesize existing evidence on the association between burnout and suicidality in healthcare professionals and to identify vulnerable subgroups and intervention priorities.

Approach:
  • Systematic Review: Conducted in accordance with PRISMA 2020 guidelines, searching databases for studies published between January 2005 and December 2024, focusing on healthcare professionals and related high-stress occupational populations.
Key Findings:
  • A total of 29 studies met the inclusion criteria; 10 studies were included in the meta-analysis.
  • Strong associations were observed between burnout and suicidality, with emotional exhaustion and depersonalization identified as robust predictors.
  • Nurses and physicians were identified as particularly vulnerable, with higher effect sizes reported during the pandemic.
  • Overall methodological quality of the studies was moderate to high, with heterogeneity explained by profession, region, and burnout instrument.
Interpretation:

Burnout, particularly emotional exhaustion and depersonalization, is linked to increased suicidality among healthcare professionals, with evidence from related high-stress occupations.

Limitations:
  • Heterogeneity in studies regarding profession, region, and burnout assessment tools.
  • Potential biases in study designs and reporting.
Conclusion:

The findings indicate a need for systematic burnout surveillance and mental health support access for healthcare professionals.

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