Mood instability and mental health service use in autism and attention-deficit/hyperactivity disorder: a natural language processing analysis of CRIS electronic healthcare records from 21 906 children and adolescents - Summary - MDSpire

Mood instability and mental health service use in autism and attention-deficit/hyperactivity disorder: a natural language processing analysis of CRIS electronic healthcare records from 21 906 children and adolescents

  • By

  • Asilay Seker

  • Seungyoung Kim

  • Susie Chandler

  • Craig Colling

  • Rashmi Patel

  • Edmund Sonuga-Barke

  • Johnny Downs

  • June 18, 2026

  • 0 min

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Objective:

To examine the association between baseline mood instability and time to discharge and annual CAMHS use in children and young people with ASD and/or ADHD.

Approach:
  • Method: label
  • Method: text
Key Findings:
  • Mood instability was associated with increased annual CAMHS use: aIRR 1.24 for ASD, aIRR 1.47 for ADHD, and aIRR 1.27 for ASD+ADHD.
  • Mood instability did not significantly affect discharge timelines in autistic children, but was linked to reduced time to discharge in the ADHD group (aTR 0.76).
  • The association was strongest in ADHD patients not receiving medication (aIRR 1.67; aTR 0.70).
Interpretation:

Mood instability is associated with elevated CAMHS use in CYP with neurodevelopmental conditions, with varying effects across diagnostic groups.

Limitations:
  • The study may not account for all confounding factors influencing CAMHS utilization.
  • Findings are based on electronic health records, which may have limitations in data completeness and accuracy.
Conclusion:

Mood instability is linked to higher CAMHS use in CYP with neurodevelopmental conditions.

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