To characterize outcomes after spine SBRT in adults aged 70 years or older and identify predictors of local failure and vertebral compression fracture.
Approach:
Design and cohort: Retrospective analysis of a prospectively maintained database of consecutive patients treated at the University of Pittsburgh Medical Center from 2002 to 2024. The cohort included 161 patients aged 70 or older with 208 spinal metastases.
Treatment and assessment: SBRT was delivered with or without surgery, with treatment selection individualized. Outcomes included radiographic local failure, vertebral compression fracture, pain response, and radiation toxicity.
Interpretation:
The provided excerpt describes the study rationale and methods but ends before the results are reported.
Limitations:
The provided excerpt is truncated during the outcome definitions and does not include the study results or reported limitations.
by Brock J. Gjesdal, Samuel Adida, Suchet Taori, Andrew H. Zureick, Serah Choi, John C. Flickinger, Pascal O. Zinn, James C. Bayley, Peter C. Gerszten, Roberta K. Sefcik
