To identify initial positive detections of wild-type measles virus in wastewater, understand associations with clinical cases, and demonstrate significant public health impact.
Key Findings:
First positive detection of wild-type MeV in Sandoval County on April 30, 2025, with a 5-day lead time before clinical cases.
Two laboratory-confirmed measles cases in Sandoval County were reported shortly after wastewater detection.
Total of 5 detections of wild-type MeV in New Mexico during the study period, aiding in early warning and public health response, highlighting the significance of these findings.
Interpretation:
Wastewater surveillance provides early detection of measles, enabling timely public health interventions and increased vaccination uptake, which is crucial for community health.
Limitations:
Dependence on public sewer systems for effective monitoring.
Potential for transient individuals to affect detection results.
Negative detections cannot confirm absence of disease in the community, and potential biases in sampling methods should be considered.
Conclusion:
Wastewater monitoring is a valuable tool for early detection of measles, enhancing public health responses and vaccination efforts, emphasizing the importance of collaboration in these initiatives.
Data suggest fewer respiratory syncytial virus–associated hospitalizations and emergency department visits among the youngest infants during the second season of routine prevention product use.