Gestational Age as predictor of Postoperative Prognosis in Neonates with Pulmonary Atresia With Intact Ventricular Septum Undergoing Biventricular Repair - Summary - MDSpire

Gestational Age as predictor of Postoperative Prognosis in Neonates with Pulmonary Atresia With Intact Ventricular Septum Undergoing Biventricular Repair

  • By

  • Chen, Shuo

  • Zhou, Ziqin

  • Hu, Luoming

  • tu, jiazichao

  • chen, weimin

  • tian, miao

  • Deng, Xiaohua

  • Li, Xiaohua

  • Su, Zhanhao

  • Chen, Jimei

  • June 22, 2026

  • 0 min

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Objective:

To characterize the impact of gestational age on short-term outcomes after biventricular repair for pulmonary atresia with intact ventricular septum (PA/IVS).

Approach:
    Key Findings:
    • Each additional gestational week reduced adverse outcome risk by 45% (OR 0.55, 95% CI 0.41-0.75).
    • Term infants had a significantly lower risk of adverse outcomes compared to preterm infants (OR 0.14, 95% CI 0.04-0.46).
    • A nonlinear threshold effect was identified with an inflection point at 37.6 weeks gestation.
    Interpretation:

    Extending gestation beyond 37.6 weeks significantly improves short-term outcomes in PA/IVS patients undergoing biventricular repair.

    Conclusion:

    The study provides evidence-based guidance for perinatal management of PA/IVS patients regarding gestational age.

Original Source(s)

Gestational Age as predictor of Postoperative Prognosis in Neonates with Pulmonary Atresia With Intact Ventricular Septum Undergoing Biventricular Repair

  • by Chen, Shuo , Zhou, Ziqin , Hu, Luoming , tu, jiazichao , chen, weimin , tian, miao , Deng, Xiaohua , Li, Xiaohua , Su, Zhanhao , Chen, Jimei

  • June 22, 2026

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