Studies on allergic diseases and B cells in the past 20 years: a bibliometric analysis via CiteSpace and VOSviewer - Summary - MDSpire

Studies on allergic diseases and B cells in the past 20 years: a bibliometric analysis via CiteSpace and VOSviewer

  • By

  • Weiyuan Mai

  • Xiaoqu Chen

  • Wanlin Ye

  • Guangshen Zhang

  • Wenyu Liang

  • May 14, 2026

  • 0 min

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Objective:

To analyze the bibliometric trends in research related to B cells and allergic diseases over the past two decades, highlighting the significance of these trends in advancing understanding and treatment.

Key Findings:
  • Annual publications and citations have consistently increased, indicating growing scholarly engagement.
  • Research is primarily concentrated in allergy and immunology journals from Europe and the U.S., with increasing contributions from other regions.
  • Emerging research areas include regulatory B cells and innate lymphoid cells, reflecting a shift in focus.
  • There is a growing translational interest in B-cell-related interventions for allergic disorders, suggesting potential for new therapeutic approaches.
Interpretation:

The study indicates a shift from basic IgE correlation studies to a deeper understanding of B-cell biology and its implications in allergic diseases, which may inform future research directions.

Limitations:
  • The study is limited to publications indexed in specific databases, which may not capture all relevant research.
  • Potential biases in publication trends based on regional contributions could affect the comprehensiveness of the findings.
Conclusion:

Future research should focus on multicenter trials with standardized B-cell phenotyping and functional outcomes to advance precision medicine in allergy treatment, particularly in under-researched areas.

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