When to trust the answer: question-aligned semantic nearest neighbor entropy for safer surgical VQA - Summary - MDSpire

Determining Reliability in Surgical Visual Question Answering: Utilizing Question-Aligned Semantic Nearest Neighbor Entropy for Enhanced Safety

  • By

  • Luca Carlini

  • Dennis Pierantozzi

  • Mauro Orazio Drago

  • Chiara Lena

  • Cesare Hassan

  • Elena De Momi

  • Danail Stoyanov

  • Sophia Bano

  • Mobarak I. Hoque

  • July 17, 2026

Share

Objective:

To enhance safety in surgical Visual Question Answering (VQA) by developing a failure detection method that incorporates question alignment into uncertainty estimation for preclinical evaluation.

Approach:
  • QA-SNNE Development: Introduced question-aligned semantic nearest neighbor entropy (QA-SNNE) as a black-box failure-detection score that combines answer consistency with question alignment.
  • Out-of-template Evaluation: Constructed an out-of-template version of EndoVis18-VQA by rephrasing question templates while preserving images, answers, and splits to test model stability under varied wording.
  • Evaluation Metrics: Evaluated QA-SNNE against existing methods (DSE, SNNE, VL-U) using AUROC, calibrated accuracy, sensitivity, and specificity across zero-shot and PEFT surgical VQA models.
Key Findings:
  • QA-SNNE effectively captures both answer consistency and question validity, addressing limitations of existing methods.
  • The out-of-template evaluation revealed that models may not perform reliably under varied question phrasing.
  • QA-SNNE demonstrated improved failure detection compared to traditional methods.
Interpretation:

The study highlights the integration of question alignment into uncertainty estimation for surgical VQA.

Limitations:
  • The study does not claim clinical validation or routine deployment of the proposed methods.
  • Evaluation is based on a controlled dataset, which may not fully represent real-world variability in clinical language.
Conclusion:

QA-SNNE improves the reliability of surgical VQA systems by addressing both answer consistency and question relevance.

Original Source(s)

Related Content