The effect of acceptance and commitment therapy on negative emotions and quality of life in stroke patients: a systematic review and meta-analysis - Summary - MDSpire

The effect of acceptance and commitment therapy on negative emotions and quality of life in stroke patients: a systematic review and meta-analysis

  • By

  • Yana Wang

  • Boling Wei

  • Lu Wang

  • Chun Huang

  • Jifeng Rong

  • Tianbao Sun

  • Yu Liu

  • May 18, 2026

  • 0 min

Share

Objective:

To evaluate the efficacy of acceptance and commitment therapy (ACT)-based interventions (including ACT alone or ACT combined with conventional rehabilitation) in improving negative emotions and quality of life in stroke patients compared to conventional rehabilitation.

Key Findings:
  • ACT significantly alleviated depression (SMD = −1.37, 95% CI −1.86 to −0.87, p < 0.00001) and anxiety (SMD = −1.25, 95% CI: −1.76 to −0.74, p < 0.00001) compared to control interventions.
  • ACT enhanced quality of life (SMD = 1.36, 95% CI: 0.69 to 2.02, p < 0.0001).
  • Positive effects were observed on psychological flexibility, self-efficacy, sleep quality, and activities of daily living.
Interpretation:

ACT is effective in reducing depression and anxiety while improving quality of life among stroke survivors, addressing multiple psychological and functional domains.

Limitations:
  • Variability in ACT intervention protocols across studies.
  • Small sample sizes in some included studies.
  • Potential biases in study selection and data extraction.
  • Lack of standardized outcome measurements across studies.
Conclusion:

ACT demonstrates significant benefits for emotional well-being and quality of life in stroke patients, warranting further large-scale, high-quality RCTs with standardized protocols to confirm long-term efficacy.

Original Source(s)

Related Content