Performance of Tai Chi Chuan and NF-κB-driven proinflammatory gene expression (IL-6, IL-1β, TNF-α) in adult chronic disease patients: a systematic review and meta-analysis of randomized controlled trials - Takeaways - MDSpire

Performance of Tai Chi Chuan and NF-κB-driven proinflammatory gene expression (IL-6, IL-1β, TNF-α) in adult chronic disease patients: a systematic review and meta-analysis of randomized controlled trials

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  • 1

    Tai Chi Chuan significantly reduces pro-inflammatory gene expression in adults with chronic diseases, particularly IL-6 and IL-1β.

  • 2

    The systematic review included 20 randomized controlled trials across various disease systems, demonstrating Tai Chi's broad applicability.

  • 3

    Subgroup analysis indicated that patients with endocrine and respiratory diseases experienced the most significant benefits from Tai Chi.

  • 4

    Tai Chi Chuan is shown to be a safe and feasible intervention for alleviating systemic inflammation linked to chronic illnesses.

  • 5

    Future research should focus on randomized controlled trials measuring NF-κB core proteins to better understand Tai Chi's regulatory effects.

Original Source(s)

Performance of Tai Chi Chuan and NF-κB-driven proinflammatory gene expression (IL-6, IL-1β, TNF-α) in adult chronic disease patients: a systematic review and meta-analysis of randomized controlled trials

  • by Si-Qi Zhu, Hong Wang

  • May 5, 2026

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