Gut microbiota modulation in the prevention and treatment of heat stroke - Takeaways - MDSpire

Gut microbiota modulation in the prevention and treatment of heat stroke

  • By

  • Zhenglian Wang

  • Jun Yan

  • Jing Xiao

  • Weijun Guo

  • Maolin Deng

  • June 2, 2026

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  • 1

    Heat stroke (HS) is increasingly prevalent due to climate change, characterized by rapid temperature elevation and potential organ failure.

  • 2

    Intestinal injury plays a critical role in HS pathogenesis, leading to increased permeability and systemic inflammation.

  • 3

    Heat-induced gut dysbiosis results in reduced beneficial bacteria and overgrowth of pathogens, contributing to mucosal inflammation.

  • 4

    Probiotics may help mitigate HS severity by enhancing gut microbiota balance and improving intestinal barrier function.

  • 5

    Current evidence on gut microbiota's role in HS primarily comes from animal studies, necessitating cautious interpretation for human application.

Original Source(s)

Gut microbiota modulation in the prevention and treatment of heat stroke

  • by Zhenglian Wang, Jun Yan, Jing Xiao, Weijun Guo, Maolin Deng

  • June 2, 2026

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