Integrated biomarkers and cardiac phenotypes associated with atrial fibrillation: evidence from real-world hospital data - Takeaways - MDSpire

Integrated biomarkers and cardiac phenotypes associated with atrial fibrillation: evidence from real-world hospital data

  • By

  • Xuli Chen

  • Yanxi Ning

  • Yuxiang Wang

  • Yuelin Hu

  • Yanchao Liu

  • Wenwen Xiao

  • May 15, 2026

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  • 1

    The study analyzed the association between BNP/LVEF and atrial fibrillation in 270 hospitalized patients.

  • 2

    Higher BNP/LVEF values were independently linked to an increased risk of atrial fibrillation, with an OR of 1.02.

  • 3

    A significant non-linear relationship was found, with risk increasing sharply at lower BNP/LVEF levels.

  • 4

    BNP/LVEF demonstrated good discriminatory ability for atrial fibrillation, with an AUC of 0.84.

  • 5

    Subgroup analysis revealed significant heterogeneity in AF risk based on sex, smoking, alcohol consumption, and coronary heart disease.

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