Case Report: Contrast-enhanced ultrasonography for evaluating a newly detected contralateral pulmonary lesion during non-small cell lung cancer chemoimmunotherapy - Takeaways - MDSpire

Case Report: Contrast-enhanced ultrasonography for evaluating a newly detected contralateral pulmonary lesion during non-small cell lung cancer chemoimmunotherapy

  • By

  • Yang Liu

  • Lusi Feng

  • Xiaoqian Yang

  • Shiyu Wen

  • Yu Xiang

  • Xuelei Ma

  • Rongxing Zhou

  • Wei Du

  • May 21, 2026

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  • 1

    New pulmonary lesions during chemoimmunotherapy for NSCLC can indicate tumor progression, infection, or benign processes, complicating diagnosis.

  • 2

    Contrast-enhanced ultrasonography (CEUS) provides real-time perfusion information, aiding in the characterization of peripheral pulmonary lesions.

  • 3

    In a case study, CEUS suggested an inflammatory nature for a newly detected contralateral lesion in a patient undergoing NSCLC treatment.

  • 4

    The interpretation of CEUS findings was supported by microbiologic evidence of infection and confirmed by lesion regression after treatment.

  • 5

    CEUS is most effective when combined with clinical, laboratory, microbiologic, and imaging data, rather than used alone for diagnosis.

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