Impact of frailty on post-procedural adverse outcomes in older adults aged ≥75 years undergoing percutaneous coronary intervention: a systematic review of observational studies - Takeaways - MDSpire

Impact of frailty on post-procedural adverse outcomes in older adults aged ≥75 years undergoing percutaneous coronary intervention: a systematic review of observational studies

  • By

  • Peng Tian

  • Liping Wang

  • Tianjiao He

  • Qiurong Zhang

  • Yingying Cai

  • May 14, 2026

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  • 1

    Frailty significantly increases the risk of in-hospital and all-cause mortality in patients aged ≥75 years undergoing PCI.

  • 2

    Frail patients aged ≥75 years have a higher incidence of complications, including bleeding and stroke, following PCI.

  • 3

    The systematic review included 18 cohort studies with over 2 million patients, highlighting the prevalence of frailty in elderly PCI patients.

  • 4

    The GRADE evidence quality for outcomes related to frailty and PCI was rated low, indicating uncertainty in the findings.

  • 5

    Findings support the need for perioperative risk stratification and individualized management in elderly patients undergoing PCI.

Original Source(s)

Impact of frailty on post-procedural adverse outcomes in older adults aged ≥75 years undergoing percutaneous coronary intervention: a systematic review of observational studies

  • by Peng Tian, Liping Wang, Tianjiao He, Qiurong Zhang, Yingying Cai

  • May 14, 2026

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