Plasma haem oxygenase-1 and interleukin-6 as adjunct host biomarkers associated with malaria - Takeaways - MDSpire

Plasma haem oxygenase-1 and interleukin-6 as adjunct host biomarkers associated with malaria

  • By

  • Theophilus Wakai

  • Irrinus Kintung

  • Temitayo Ogundimu

  • Shalom Chinedu

  • Israel Afolabi

  • May 15, 2026

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  • 1

    Haem oxygenase-1 (HO-1) and interleukin-6 (IL-6) are explored as complementary biomarkers in malaria-endemic populations.

  • 2

    Microscopy-positive individuals showed significantly lower blood indices and higher inflammatory markers compared to microscopy-negative individuals.

  • 3

    IL-6 levels were significantly higher in malaria-positive individuals, indicating its potential as a valuable inflammatory biomarker.

  • 4

    HO-1 demonstrated limited differences across groups, suggesting its role as a biomarker requires further investigation.

  • 5

    IL-6 exhibited superior discriminatory ability over HO-1, highlighting its relevance in assessing malaria-related physiological changes.

Original Source(s)

Plasma haem oxygenase-1 and interleukin-6 as adjunct host biomarkers associated with malaria

  • by Theophilus Wakai, Irrinus Kintung, Temitayo Ogundimu, Shalom Chinedu, Israel Afolabi

  • May 15, 2026

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