Brain cortex activity of patients with disorders of consciousness under familiar and unfamiliar voice of subject's own name: an fNIRS-based study - Takeaways - MDSpire

Brain cortex activity of patients with disorders of consciousness under familiar and unfamiliar voice of subject's own name: an fNIRS-based study

  • By

  • Jinqin Zhang

  • Zhihong Jiao

  • Fubiao Huang

  • Xinping Wang

  • Xindiao Zhou

  • Qing Li

  • Ying Zhang

  • Liping Long

  • Yinuo Su

  • Kexin Cao

  • Yiheng Han

  • June 4, 2026

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  • 1

    This study utilized fNIRS to assess cortical activation in patients with disorders of consciousness (DOC) in response to familiar and unfamiliar voices.

  • 2

    Participants with DOC showed distinct cortical activation patterns when stimulated by familiar versus unfamiliar voices calling their name.

  • 3

    Under unfamiliar voice stimulation, participants exhibited deactivation in the Left Dorsolateral Pre-frontal Cortex (DLPFC-L).

  • 4

    Cortical responses to familiar voice stimulation were positively correlated with the Coma Recovery Scale-Revised (CRS-R) scores.

  • 5

    The findings suggest that auditory stimulation strategies may need to be personalized for effective rehabilitation in DOC patients.

Original Source(s)

Brain cortex activity of patients with disorders of consciousness under familiar and unfamiliar voice of subject's own name: an fNIRS-based study

  • by Jinqin Zhang, Zhihong Jiao, Fubiao Huang, Xinping Wang, Xindiao Zhou, Qing Li, Ying Zhang, Liping Long, Yinuo Su, Kexin Cao, Yiheng Han

  • June 4, 2026

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