Left atrial strain parameters for predicting new-onset atrial fibrillation: a systematic review and meta-analysis - Takeaways - MDSpire

Left atrial strain parameters for predicting new-onset atrial fibrillation: a systematic review and meta-analysis

  • By

  • Haijian Yang

  • Youfu He

  • Lei Peng

  • Deqi Wang

  • Jun Yang

  • Linfeng Yin

  • June 3, 2026

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  • 1

    Left atrial strain parameters (LASPs) are evaluated by speckle tracking echocardiography to predict new-onset atrial fibrillation (NOAF).

  • 2

    The meta-analysis included 39 studies with 20,681 subjects, revealing significant associations between low LASPs and increased risk of NOAF.

  • 3

    PALS, LASr, LAScd, and LASct showed risk ratios indicating that lower values correlate with a higher likelihood of developing NOAF.

  • 4

    The summary receiver operating characteristic curve analysis indicated good diagnostic performance for PALS, LASr, and LASct with AUCs of 0.84, 0.84, and 0.78, respectively.

  • 5

    This study supports the use of LASPs as diagnostic tools for evaluating and predicting the risk of NOAF in clinical practice.

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