Lipid feature and late onset ≥80 years of ischemic stroke: a retrospective study in lipid-lowering therapy-naive adults

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The study analyzed lipid profiles in treatment-naive adults aged 80 and above experiencing first-onset ischemic stroke.
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The oldest-old group exhibited significantly lower levels of total cholesterol, triglycerides, and LDL-C compared to younger cohorts.
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Non-HDL-C was identified as the primary lipid predictor of late-onset ischemic stroke, with gender-specific differences in lipid predictors.
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The research highlights the unique lipid patterns in the elderly, emphasizing the need for tailored prevention strategies.
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Findings suggest that public health initiatives should prioritize non-HDL-C alongside LDL-C in lipid regulation efforts.

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