Case Report: A case of diffuse subretinal fibrosis and uveitis syndrome with vitreoretinal traction syndrome - Takeaways - MDSpire

Case Report: A case of diffuse subretinal fibrosis and uveitis syndrome with vitreoretinal traction syndrome

  • By

  • Xiaohua Zhang

  • Yongping Hu

  • Jian Li

  • May 7, 2026

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  • 1

    A 67-year-old female was diagnosed with bilateral diffuse subretinal fibrosis and uveitis syndrome, complicated by vitreoretinal traction syndrome.

  • 2

    The patient experienced a 4-year gap between the onset of symptoms in each eye, highlighting the sequential nature of the condition.

  • 3

    Fundus examination revealed significant retinal changes, including yellowish-white subretinal lesions and neovascularization in the left eye.

  • 4

    Treatment involved pars plana vitrectomy, glucocorticoids, immunosuppressive therapy, and anti-VEGF therapy for recurrent macular edema.

  • 5

    The case emphasizes the diagnostic challenges of SFU syndrome and the need for comprehensive management strategies due to its poor prognosis.

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