Caries May May Signal Oral Antibiotic Resistance

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Patients with active dental caries exhibit species-specific differences in antibiotic resistance compared to those with good oral health.
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In a study of 319 bacterial isolates, significant differences in susceptibility to ampicillin were found in Veillonella parvula between caries and healthy patients.
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Biofilm formation varied, with 79% of isolates from caries patients classified as moderate biofilm producers, while 82% from healthy patients were non-biofilm producers.
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Resistant isolates were identified across multiple taxa, including Streptococcus oralis and Fusobacterium nucleatum, with beta-lactamase activity confirmed in some.
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The study's findings indicate that associations between caries and antibiotic resistance are species-specific and not universally applicable across all taxa.

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