Systemic inflammation and extra-articular manifestations in rheumatoid arthritis: a cross-sectional study - Takeaways - MDSpire

Systemic inflammation and extra-articular manifestations in rheumatoid arthritis: a cross-sectional study

  • By

  • Karlygash Sadykova

  • Gulnaz Nuskabayeva

  • Ainash Oshibayeva

  • Shakhnoza Tatykayeva

  • Elmira Iskandirova

  • Arzu Mamutova

  • Aziza Djurabekova

  • Ugilzhan Tatykayeva

  • May 15, 2026

Share

  • 1

    A cross-sectional study involving 299 RA patients identified extra-articular manifestations in 93% of participants.

  • 2

    Older age and higher disability prevalence were significantly associated with extra-articular manifestations in RA patients.

  • 3

    Elevated systemic inflammation markers, including ESR and CRP, correlated with the presence of extra-articular manifestations.

  • 4

    Multivariable analysis indicated that ESR was independently linked to extra-articular manifestations, while elevated WBC count was inversely correlated.

  • 5

    The study emphasizes the need for monitoring chronic inflammation in RA to understand the implications of extra-articular symptoms.

Original Source(s)

Systemic inflammation and extra-articular manifestations in rheumatoid arthritis: a cross-sectional study

  • by Karlygash Sadykova, Gulnaz Nuskabayeva, Ainash Oshibayeva, Shakhnoza Tatykayeva, Elmira Iskandirova, Arzu Mamutova, Aziza Djurabekova, Ugilzhan Tatykayeva

  • May 15, 2026

Related Content