Editorial: Metabolic and biomechanical factors in bone fragility: new frontiers in understanding and managing osteoporosis

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Skeletal fragility primarily results from loss of bone mass and structural changes that reduce bone quality and strength.
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Osteoporosis can be classified as primary or secondary, with secondary causes affecting many postmenopausal and premenopausal individuals.
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Research advancements focus on understanding bone loss pathophysiology, assessing fracture risk, and developing new therapeutic approaches.
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The editorial highlights the importance of integrating lifestyle modifications and addressing secondary causes in osteoporosis management.
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Effective osteoporosis management requires accurate fracture prediction tools and tailored treatment modalities based on specific bone loss mechanisms.

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