Safety Framework for Gastric Mucosal Ablation (GMA) Using Hybrid Argon Plasma Coagulation (hAPC): International Expert Consensus - Takeaways - MDSpire

Safety Framework for Gastric Mucosal Ablation (GMA) Using Hybrid Argon Plasma Coagulation (hAPC): International Expert Consensus

  • By

  • Vivek Kumbhari

  • Adrian Sartoretto

  • Ivo Boskoski

  • Diogo de Moura

  • Dilhana Badurdeen

  • Daniel Maselli

  • Eduardo de Moura

  • Valerio Pontecorvi

  • Barham Abu Dayyeh

  • Christopher McGowan

  • May 16, 2026

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  • 1

    Gastric mucosal ablation (GMA) is an investigational endoscopic technique aimed at reducing appetite and promoting weight loss.

  • 2

    GMA utilizes hybrid argon plasma coagulation (hAPC) to safely ablate mucosa while protecting deeper gastric layers.

  • 3

    Standardized safety protocols are essential to minimize risks such as deep tissue injury and delayed hemorrhage during GMA.

  • 4

    The expert consensus outlines nine key safety tenets for GMA, including proper saline injection and gradual dietary advancement post-procedure.

  • 5

    The framework developed by international experts aims to guide safe GMA practices within clinical investigations, not routine clinical use.

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