Acute retinal necrosis presenting exudative retinal detachment: a case report - Takeaways - MDSpire
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Exudative Retinal Detachment as an Early Manifestation of Acute Retinal Necrosis: A Case Study

  • By

  • Han Wang

  • Ying Zhu

  • Ai Xuan Cheng

  • Chao Zhang

  • June 24, 2026

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  • 1

    Acute retinal necrosis (ARN) is a severe viral retinitis that can lead to retinal detachment, but exudative retinal detachment (ERD) is a rare early manifestation.

  • 2

    A 43-year-old woman presented with acute blurred vision and ocular pain, initially diagnosed with ERD without clear evidence of retinal necrosis.

  • 3

    Metagenomic testing confirmed varicella zoster virus (VZV) infection after characteristic retinal necrotic lesions appeared following corticosteroid treatment.

  • 4

    The patient received aggressive antiviral therapy, including intravenous acyclovir and intravitreal ganciclovir, leading to resolution of retinal detachment.

  • 5

    This case highlights the importance of considering viral infections in uveitis patients with ERD who do not respond to initial anti-inflammatory treatments.

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