Disrupted sensory interhemispheric synchronization in schizophrenia: a frequency-resolved VMHC analysis

1

Patients with schizophrenia showed significantly reduced voxel-mirrored homotopic connectivity (VMHC) in sensory networks compared to healthy controls.
2

Frequency-specific analyses indicated higher VMHC at slow-5 compared to slow-4 in visual gyrus and subcortical regions among patients.
3

Significant group-by-frequency interactions were found in the middle occipital gyrus and postcentral gyrus, with reduced slow-4 VMHC in schizophrenia.
4

The study highlights frequency-dependent reductions of interhemispheric connectivity in schizophrenia, particularly affecting sensory systems.
5

Findings suggest that frequency-resolved VMHC analyses can enhance understanding of network dysfunction in schizophrenia.

1