Adjunctive ab-interno goniotomy in chronic angle-closure glaucoma: a retrospective proof-of-concept pilot study using doubly robust learning - Takeaways - MDSpire

Adjunctive ab-interno goniotomy in chronic angle-closure glaucoma: a retrospective proof-of-concept pilot study using doubly robust learning

  • By

  • YuQi Ren

  • Xiaojing Zha

  • YiZheng Zhang

  • Jin Xuan

  • ZhiYong Meng

  • ChenMing Zhang

  • June 19, 2026

  • 0 min

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  • 1

    The study evaluated the effectiveness of adjunctive ab-interno goniotomy during phacoemulsification with goniosynechialysis in chronic angle-closure glaucoma.

  • 2

    A total of 102 eyes were analyzed, with 54 receiving Phaco-GSL alone and 48 receiving adjunctive goniotomy.

  • 3

    Adjunctive goniotomy showed higher 24-month qualified-failure-free survival compared to Phaco-GSL alone, with a weighted hazard ratio of 0.475.

  • 4

    Doubly robust estimates indicated that adjunctive goniotomy favored medication-free complete success and qualified success at 24 months.

  • 5

    The study concluded that adjunctive goniotomy may improve surgical control, but individualized benefit estimates require further validation.

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