Non-linear relationship between serum chloride concentrations and all-cause mortality at 30 and 365 days in septic patients with liver cirrhosis - Takeaways - MDSpire

Non-linear relationship between serum chloride concentrations and all-cause mortality at 30 and 365 days in septic patients with liver cirrhosis

  • By

  • Yue Qiu

  • Xiaoqing Liu

  • Hechen Shen

  • Qiao Tang

  • Yunling Xue

  • Peng Hu

  • January 20, 2026

  • 0 min

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  • 1

    Septic patients with liver cirrhosis have a poor prognosis and complex management due to their compromised immune systems.

  • 2

    Serum chloride is a critical marker for fluid management and has been linked to mortality in various systemic diseases.

  • 3

    This study analyzed data from the MIMIC-IV database to investigate the relationship between serum chloride levels and mortality.

  • 4

    The primary outcome measured was 30-day all-cause mortality, with secondary outcomes at 60 and 365 days.

  • 5

    Findings aim to provide clinicians with a novel prognostic indicator to enhance treatment strategies for these patients.

Original Source(s)

Non-linear relationship between serum chloride concentrations and all-cause mortality at 30 and 365 days in septic patients with liver cirrhosis

  • by Yue Qiu, Xiaoqing Liu, Hechen Shen, Qiao Tang, Yunling Xue, Peng Hu

  • January 20, 2026

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