Heart failure in patients with recently diagnosed atrial fibrillation: findings from the GLORIA-AF Registry Phase III - Takeaways - MDSpire

Heart failure in patients with recently diagnosed atrial fibrillation: findings from the GLORIA-AF Registry Phase III

  • By

  • Bernadette Corica

  • Giulio Francesco Romiti

  • Marco Proietti

  • Giuseppe Boriani

  • Brian Olshansky

  • Menno V Huisman

  • Gregory Y H Lip

  • on behalf of the GLORIA-AF Investigators

  • September 1, 2025

  • 0 min

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  • 1

    Congestive heart failure (CHF) is present in 21.9% of patients recently diagnosed with atrial fibrillation (AF) in the GLORIA-AF Registry.

  • 2

    Patients with CHF and left ventricular ejection fraction (LVEF) ≤ 40% are more likely to receive oral anticoagulants compared to those with LVEF > 40%.

  • 3

    Non-vitamin K oral anticoagulants are less frequently used in patients with CHF, regardless of their left ventricular ejection fraction.

  • 4

    CHF significantly increases the risk of all-cause death and major adverse cardiovascular events in patients with AF, especially with LVEF ≤ 40%.

  • 5

    The coexistence of AF and CHF indicates a need for tailored interventions to improve patient outcomes and management strategies.

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