A preliminary study on brain functional magnetic resonance imaging in migraine patients with visual aura using visual stimulation

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The study investigates brain fMRI responses to visual stimulation in migraine patients with visual aura (VaM) and without aura (MwoA).
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A total of 63 participants were recruited, including 21 VaM patients, 21 MwoA patients, and 21 healthy controls, all undergoing BOLD-fMRI scanning.
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Significant brain activation differences were observed among the VaM, MwoA, and healthy control groups in various brain regions, including the precuneus and cuneus.
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The VaM group exhibited stronger activation in the left precuneus compared to healthy controls, while the MwoA group showed stronger activation in the middle occipital gyrus.
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Abnormalities in visual-related brain networks suggest a central mechanism for visual aura generation in VaM, warranting further investigation into its pathogenesis.

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