Intraoperative radiotherapy after neurosurgical resection of brain metastases as institutional standard treatment– update of the oncological outcome form a single center cohort after 117 procedures

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Intraoperative radiotherapy (IORT) with 50 kV x-rays is increasingly used after neurosurgical resection of brain metastases for improved local control.
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The study analyzed 105 patients treated with IORT, showing a median overall survival of 18.2 months and a 1-year survival rate of 57.7%.
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The local control rate of the resection cavity was 90.5%, with an estimated 1-year local control rate of 84.2%.
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Distant brain control was observed in 61.9% of patients, with an estimated 1-year distant control rate of 47.9%.
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Only 16% of patients required whole brain irradiation post-treatment, indicating the effectiveness of IORT in managing brain metastases.

Journal Of Neuro-Oncology

by Klaus-Henning Kahl, Philipp E. Krauss, Maria Neu, Christoph J. Maurer, Sabine Schill-Reiner, Zoha Roushan, Eva Laukmanis, Christian Dobner, Tilman Janzen, Nikolaos Balagiannis, Björn Sommer, Georg Stüben, Ehab Shiban
July 4, 2024

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